Alan H Jobe Selected Research

Interleukin-6 (Interleukin 6)

1/2016	Pulmonary Morbidity in Infancy after Exposure to Chorioamnionitis in Late Preterm Infants.
9/2014	Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma parvum from the amniotic fluid in an ovine model of intrauterine infection.
5/2009	IL-1 mediates pulmonary and systemic inflammatory responses to chorioamnionitis induced by lipopolysaccharide.
4/2009	Intra-amniotic LPS modulation of TLR signaling in lung and blood monocytes of fetal sheep.

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Alan H Jobe Research Topics

Disease

71	Inflammation (Inflammations) 10/2023 - 02/2002
58	Chorioamnionitis 02/2024 - 01/2002
38	Pneumonia (Pneumonitis) 10/2023 - 02/2002
30	Lung Injury 02/2024 - 06/2002
25	Bronchopulmonary Dysplasia 10/2023 - 03/2002
23	Premature Birth (Birth, Premature) 01/2024 - 05/2002
20	Infections 09/2023 - 10/2010
14	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2024 - 11/2002
8	Premature Obstetric Labor (Premature Labor) 01/2022 - 01/2002
6	Acute-Phase Reaction 01/2018 - 12/2009
4	Brain Injuries (Brain Injury) 10/2023 - 04/2004
4	Perinatal Death 11/2022 - 04/2004
4	Lung Diseases (Lung Disease) 01/2022 - 01/2010
3	Birth Weight (Birth Weights) 01/2022 - 01/2003
3	Fetal Weight 01/2021 - 11/2003
3	Hyperoxia 01/2020 - 12/2009
3	Ureaplasma Infections (Ureaplasma Infection) 01/2017 - 09/2010
3	Stillbirth 06/2016 - 12/2011
3	Acidosis 06/2010 - 05/2002
3	Body Weight (Weight, Body) 05/2010 - 03/2002
2	Respiratory Insufficiency (Respiratory Failure) 01/2021 - 11/2019
2	Pre-Eclampsia (Preeclampsia) 01/2021 - 05/2011
2	Hyaline Membrane Disease 01/2020 - 02/2015
2	Asphyxia (Suffocation) 08/2017 - 08/2015
2	Hypertrophy 01/2016 - 12/2004
2	Hypothermia 01/2009 - 10/2005
2	Vascular Remodeling 01/2007 - 12/2004
2	Fibrosis (Cirrhosis) 01/2007 - 12/2004
1	Infant Death 01/2024
1	Cardiovascular Diseases (Cardiovascular Disease) 11/2023
1	COVID-19 01/2021

Drug/Important Bio-Agent (IBA)

32	Surface-Active Agents (Surfactants)IBA 02/2024 - 03/2002
31	CytokinesIBA 01/2022 - 03/2003
30	LipopolysaccharidesIBA 11/2023 - 08/2005
28	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2023 - 11/2003
23	EndotoxinsIBA 03/2011 - 02/2002
19	Betamethasone (Celestone)FDA Link 01/2022 - 01/2002
19	Messenger RNA (mRNA)IBA 01/2021 - 03/2003
16	SteroidsIBA 02/2024 - 04/2003
13	Proteins (Proteins, Gene)FDA Link 09/2014 - 06/2002
12	Interleukin-1 (Interleukin 1)IBA 01/2018 - 03/2002
9	Budesonide (Pulmicort)FDA LinkGeneric 02/2024 - 11/2003
9	Oxygen (Dioxygen)IBA 01/2021 - 12/2009
8	Interleukin-8 (Interleukin 8)IBA 01/2017 - 11/2003
8	GlucocorticoidsIBA 03/2013 - 01/2002
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 07/2003
5	InterleukinsIBA 01/2021 - 09/2014
5	Anti-Bacterial Agents (Antibiotics)IBA 08/2017 - 10/2010
4	LigandsIBA 01/2018 - 04/2009
4	LipidsIBA 01/2017 - 06/2002
4	AntigensIBA 01/2017 - 09/2010
4	Interleukin-6 (Interleukin 6)IBA 01/2016 - 04/2009
3	Saline SolutionIBA 01/2021 - 10/2002
3	ChemokinesIBA 01/2017 - 03/2003
3	Erythromycin (Erycette)FDA LinkGeneric 08/2014 - 10/2010
3	Interleukin-1alpha (Interleukin 1 alpha)IBA 09/2006 - 03/2002
3	acivicin (AT 125)IBA 01/2003 - 08/2002
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	betamethasone sodium phosphate FDA LinkGeneric 01/2022 - 01/2018
2	IronIBA 01/2021 - 01/2020
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2021
2	gamma-sitosterol (beta-sitosterol)IBA 05/2020 - 04/2019
2	campesterolIBA 05/2020 - 04/2019
2	Phytosterols (Plant Sterols)IBA 05/2020 - 04/2019
2	Peroxidase (Myeloperoxidase)IBA 04/2019 - 05/2009
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2017 - 11/2016
2	Virulence Factors (Pathogenicity Factors)IBA 01/2017 - 01/2012
2	CollagenIBA 01/2016 - 12/2004
2	Fluconazole (Zonal)FDA LinkGeneric 01/2016 - 06/2015
2	Oxidants (Oxidizing Agents)IBA 01/2015 - 03/2008
2	Acute-Phase Proteins (Acute-Phase Protein)IBA 09/2013 - 12/2005
2	Transforming Growth Factors (Transforming Growth Factor)IBA 03/2013 - 01/2007
2	Hydrocortisone (Cortisol)FDA LinkGeneric 02/2011 - 01/2003
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2011 - 04/2009
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 05/2009 - 11/2005
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 04/2009 - 03/2003
2	AT 130IBA 05/2005 - 03/2004
1	Small Nuclear RNA (snRNA)IBA 01/2024
1	Insulin-Like PeptidesIBA 05/2023
1	Insulin-Like Growth Factor I (IGF-1)IBA 05/2023
1	Insulin (Novolin)FDA Link 05/2023
1	Acetates (Acetic Acid Esters)FDA Link 01/2022
1	betamethasone acetate FDA LinkGeneric 01/2022
1	Proto-Oncogene Proteins c-etsIBA 02/2021
1	poractant alfa (Curosurf)FDA Link 01/2021
1	2-methylpentaneIBA 01/2021
1	Volatile Organic CompoundsIBA 01/2021
1	Granulocyte-Macrophage Colony-Stimulating Factor Receptors (GM-CSF Receptor)IBA 01/2021
1	Interferon Type IIBA 01/2021

Therapy/Procedure

28	Artificial Respiration (Mechanical Ventilation) 10/2023 - 02/2002
16	Therapeutics 01/2024 - 01/2002
8	Resuscitation 08/2017 - 10/2005
3	Continuous Positive Airway Pressure 01/2024 - 09/2002
3	Aftercare (After-Treatment) 11/2022 - 10/2002
2	Prenatal Care (Care, Prenatal) 12/2011 - 05/2011
2	Injections 12/2007 - 01/2002
1	Mechanical Ventilators (Ventilator) 01/2024
1	Off-Label Use 01/2021
1	Bronchoscopes 01/2021
1	Catheters 01/2021